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Duo of complementary serums inspired by aesthetic medicine for skin that looks five years younger in just one day.
Control the passage of time with Bio-Performance Skin Filler, a duo of complementary serums, night and day, formulated with Shiseido's most futuristic technology, Molecushift, inspired by aesthetic medicine.
Step 1: Infill Night Serum: Contains compacted high molecular weight hyaluronic acid so that it can intensely penetrate the epidermis** during the night.
Step 2: Full Expansion Serum Day: Expands high molecular weight Hyaluronic Acid molecules. The high molecular weight Hyaluronic Acid molecules recover their original size to obtain a greater volume from the inside.
Benefits:
Fills wrinkles from the inside for skin that looks five years younger, with greater volume and less visible deep wrinkles in just one day*.
With over 30 years of hyaluronic acid innovation, MolecuShift technology plumps the skin from the inside to instantly firm it and reduce deep wrinkles.
*Consumer test on 110 women.
**in upper layers of the epidermis"
How to use:
Remove the outer cap and turn counterclockwise to remove it from the outer container.
Turn the dispenser to the left again to remove it from refilling.
Remove the cap from the new refill and insert the dispenser. Turn right and set.
Insert the new refill along with the dispenser into the outer container and turn clockwise until it clicks.
*Hold the dispenser well when removing or placing it in the outer container. Rotating the dispenser head may render it unusable.
Thanks to Molecushift technology, Bio-Performance Skinfiller has achieved that the compacted high molecular weight hyaluronic acid penetrates the skin and reexpands until it recovers its original size to generate an instant volumizing effect that plumps the skin from the inside.
Effects:
93% of women notice their skin has more volume.
91% of women notice their skin is firmer.
82% of women notice that their expression lines are less visible.
80% of women notice that their deep wrinkles are less visible.
The lists of ingredients contained in the composition of the products are updated regularly. Check the ingredient list on the packaging before using the product.
Fast delivery, excellent quality products, affordable prices and online ordering. I couldn’t afford to buy in-store.
Translated by Google
Gender: Woman
Age: ---
Country: FR
Has been using this product for: Less than 6 months
Skin Type:
Dry, Sensitive
dominique recommends this product
Natividad
Verified purchase
17/07/2026
I use it every day
Perfect for mature skin
Translated by Google
Gender: Woman
Age: More than 50 years old
Country: ES
Has been using this product for: Between 1 and 3 years
Skin Type:
Mixed
Natividad recommends this product
Encarnacion Peña Galindo
Verified purchase
20/05/2026
It’s my favorite cream.
I’ve been using it for a long time and I’m very satisfied with the results.
Translated by Google
Gender: Woman
Age: More than 50 years old
Country: ES
Has been using this product for: More than 5 years
Skin Type:
Mixed
Encarnacion Peña Galindo recommends this product
M ISABEL
Verified purchase
10/12/2025
HYDRATION
I’ve been using it for almost a year and I get good hydration.
Translated by Google
Gender: Woman
Age: More than 50 years old
Country: ES
Has been using this product for: Between 1 and 3 years
Skin Type:
Dry, Sensitive
M ISABEL recommends this product
maria elena
Verified purchase
14/10/2025
Correct serums
They’re not the best for my skin. They’re pleasant to use, but for mature combination skin, there are better options.
Translated by Google
Gender: Woman
Age: More than 50 years old
Country: ES
Has been using this product for: Less than 6 months
Skin Type:
Mixed, Dry
maria elena recommends this product
Yornelsy Astrid
Verified purchase
20/05/2025
This is the best thing I’ve ever used on my face.
I should say I’m delighted with this product... very happy, my skin feels more toned, its color more even and younger... also much juicier. I give it 1.3 billion out of 10.
Translated by Google
Gender: Woman
Age: Between 36 and 50 years old
Country: ES
Has been using this product for: Less than 6 months
Skin Type:
Mixed, Normal
Yornelsy Astrid recommends this product
Arnoldas
Verified purchase
28/04/2024
Wife uses
It's wonderful, I bought it in my younger days.
Translated by Google
Gender: Man
Age: Between 36 and 50 years old
Country: LT
Has been using this product for: Less than 6 months
Skin Type:
Normal, Dry
Arnoldas recommends this product
Vittoria
Verified purchase
12/03/2024
Now I only use this one!
I have been using Shiseido Bio Performance filler serum for over 1 year now, I use it continuously following the instructions in the information leaflet. It's an excellent product and the results are visible. The face is plumped up, wrinkles greatly reduced. You certainly need to be consistent and include it in your skin care routine. I don't do without it, also because it has significantly reduced the hyaluronic acid infiltrations that I used to do at the aesthetic doctor. Ultimately, since I have been using these two serums, I have no longer had any hyaluronic acid-based treatments from my aesthetic doctor. 100% satisfied and I recommend it to everyone. Perfume's service was excellent as always, punctual, precise, professional and with excellent prices
Translated by Google
Gender: Woman
Age: More than 50 years old
Country: IT
Has been using this product for: Between 1 and 3 years
Skin Type:
Normal
Vittoria recommends this product
Rufina
Verified purchase
06/03/2024
It is my favorite serum
You see the immediate effect
Translated by Google
Gender: Woman
Age: More than 50 years old
Country: ES
Has been using this product for: Between 1 and 3 years
Skin Type:
Dry
Rufina recommends this product
Derya
Verified purchase
14/02/2024
Original
I love it original product and shipping is on time thank you.
Gender: ---
Age: ---
Country: US
Has been using this product for: Less than 6 months
Sustainable packaging. Means that the wrapping or packaging is made of biodegradable, recycled or recyclable materials or allows for several useful lives, such as refillable bottles.
Refillable. Eco-designed products for multiple shelf lives and which can be refilled with the refill option once the product runs out. This is how we avoid the unnecessary consumption of resources and minimise the production of materials. A super sustainable option!
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